| PubMed ID |
|
28196983 |
Publish Date |
|
2017 Oct |
| Journal |
|
Leukemia |
Species |
|
Homo sapiens |
| Disease Type |
|
Acute lymphoblastic leukemia |
Technology |
|
Next Generation Sequencing |
| Case Number |
|
5 |
Raw Data |
|
|
| Title |
|
Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis |
| Authors |
|
Ratnaparkhe M, Hlevnjak M, Kolb T, Jauch A, Maass KK, Devens F, Rode A, Hovestadt V, Korshunov A, Pastorczak A, Mlynarski W, Sungalee S, Korbel J, Hoell J, Fischer U, Milde T, Kramm C, Nathrath M, Chrzanowska K, Tausch E, Takagi M, Taga T, Constantini S, Loeffen J, Meijerink J, Zielen S, Gohring G, Schlegelberger B, Maass E, Siebert R, Kunz J, Kulozik AE, Worst B, Jones DT, Pfister SM, Zapatka M, Lichter P, Ernst A |
| Affiliation |
|
Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany |
| Chromothripsis Definition |
|
Close-by breakpoints: >10
Copy number states: 2--3
Fragments random joining: Yes |
| Download |
|
Study Data File |
| |
| Chromothripsis Cases |
| patient_10 |
| |
|
|
| |
Case ID: |
patient_10 |
| |
Chromosome: | 14 |
| |
Disease type: |
Acute lymphoblastic leukemia |
| |
Technology: |
Next Generation Sequencing |
| |
Platform: |
Illumina HiSeq X Ten |
| | | patient_11 |
| |
|
|
| |
Case ID: |
patient_11 |
| |
Chromosome: | 22 |
| |
Disease type: |
Acute lymphoblastic leukemia |
| |
Technology: |
Next Generation Sequencing |
| |
Platform: |
Illumina HiSeq X Ten |
| | | patient_13 |
| |
|
|
| |
Case ID: |
patient_13 |
| |
Chromosome: | 14 |
| |
Disease type: |
Acute lymphoblastic leukemia |
| |
Technology: |
Next Generation Sequencing |
| |
Platform: |
Illumina HiSeq X Ten |
| | | patient_16 |
| |
|
|
| |
Case ID: |
patient_16 |
| |
Chromosome: | 21 |
| |
Disease type: |
Acute lymphoblastic leukemia |
| |
Technology: |
Next Generation Sequencing |
| |
Platform: |
Illumina HiSeq X Ten |
| | | patient_25 |
| |
|
|
| |
Case ID: |
patient_25 |
| |
Chromosome: | 14 |
| |
Disease type: |
Acute lymphoblastic leukemia |
| |
Technology: |
Next Generation Sequencing |
| |
Platform: |
Illumina HiSeq X Ten |
| | | top |
|
