| PubMed ID |
|
24413735 |
Publish Date |
|
2014 Feb |
| Journal |
|
Nature Genetics |
Species |
|
Homo sapiens |
| Disease Type |
|
Acute lymphoblastic leukemia |
Technology |
|
Next Generation Sequencing |
| Case Number |
|
1 |
Raw Data |
|
|
| Title |
|
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia |
| Authors |
|
Papaemmanuil E, Rapado I, Li Y, Potter NE, Wedge DC, Tubio J, Alexandrov LB, Van Loo P, Cooke SL, Marshall J, Martincorena I, Hinton J, Gundem G, van Delft FW5, Nik-Zainal S, Jones DR, Ramakrishna M, Titley I, Stebbings L, Leroy C, Menzies A, Gamble J, Robinson B, Mudie L, Raine K, O'Meara S, Teague JW, Butler AP, Cazzaniga G, Biondi A, Zuna J, Kempski H, Muschen M, Ford AM, Stratton MR, Greaves M, Campbell PJ |
| Affiliation |
|
Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK |
| Chromothripsis Definition |
|
Close-by breakpoints: >=30
Copy number states: 2
Fragments random joining: Yes |
| Download |
|
Study Data File |
| |
| Chromothripsis Cases |
| PD4021a |
| |
|
|
| |
Case ID: |
PD4021a |
| |
Chromosome: | X |
| |
Disease type: |
Acute lymphoblastic leukemia |
| |
Technology: |
Next Generation Sequencing |
| |
Platform: |
Illumina GAIIx |
| |
Affected Gene: |
Gene List |
| |
Download: |
Copy Number File Links File |
| |  |
|
