ChromothripsisDB: a curated database of chromothripsis
 
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  Fusion Gene
  PubMed ID: 22237106 Case ID: STJALL003 Disease: Acute lymphoblastic leukemia Genome Assembly: GRCh37/hg19
Gene Symbol 1 Chromosome1 Description 1 Gene Symbol 2 Chromosome2 Description 2
ARHGAP21 10 Rho GTPase activating protein 21 RXFP1 4 relaxin/insulin-like family peptide receptor 1
CTNNA3 10 catenin (cadherin-associated protein), alpha 3 ARHGAP21 10 Rho GTPase activating protein 21
NTNG1 1 netrin G1 ST6GALNAC5 1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
RXFP1 4 relaxin/insulin-like family peptide receptor 1 SFMBT2 10 Scm-like with four mbt domains 2
 
 
  Affected Gene
  PubMed ID: 22237106 Case ID: STJALL003 Disease: Acute lymphoblastic leukemia Genome Assembly: GRCh37/hg19
Gene Symbol Entrez Gene Chromosome Start End Description
ABCG2 9429 4 89011416 89152474 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACADM 34 1 76190036 76253260 acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACBD7 414149 10 15119522 15130775 acyl-CoA binding domain containing 7
ACTA2 59 10 90694831 90751147 actin, alpha 2, smooth muscle, aorta
ADAM30 11085 1 120436156 120439118 ADAM metallopeptidase domain 30
ADAMTS6 11174 5 64444563 64777747 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADCY2 108 5 7396321 7830194 adenylate cyclase 2 (brain)
ADO 84890 10 64564516 64568238 2-aminoethanethiol (cysteamine) dioxygenase
ADORA3 140 1 112025970 112106584 adenosine A3 receptor
AFF1 4299 4 87856154 88062206 AF4/FMR2 family, member 1
AHCYL1 10768 1 110527308 110566357 adenosylhomocysteinase-like 1
AKNAD1 254268 1 109358520 109506106 AKNA domain containing 1
ALX3 257 1 110602616 110613322 ALX homeobox 3
AMIGO1 57463 1 110046797 110052360 adhesion molecule with Ig-like domain 1
AMPD1 270 1 115215719 115238239 adenosine monophosphate deaminase 1
AMPD2 271 1 110158726 110174673 adenosine monophosphate deaminase 2
ANKRD1 27063 10 92671853 92681033 ankyrin repeat domain 1 (cardiac muscle)
ANKRD13C 81573 1 70726271 70820417 ankyrin repeat domain 13C
ANKRD22 118932 10 90581889 90611575 ankyrin repeat domain 22
ANKRD33B 651746 5 10564442 10650308 ankyrin repeat domain 33B
ANXA11 311 10 81910645 81965328 annexin A11
AP4B1 10717 1 114437370 114447823 adaptor-related protein complex 4, beta 1 subunit
ARHGAP21 57584 10 24872538 25012597 Rho GTPase activating protein 21
ARHGAP24 83478 4 86396267 86923823 Rho GTPase activating protein 24
ARL5B 221079 10 18948334 18970568 ADP-ribosylation factor-like 5B
ARMC3 219681 10 23216953 23326518 armadillo repeat containing 3
ASB17 127247 1 76384558 76398116 ankyrin repeat and SOCS box containing 17
ATAD1 84896 10 89511269 89601100 ATPase family, AAA domain containing 1
ATOH1 474 4 94750042 94751221 atonal homolog 1 (Drosophila)
ATP1A1 476 1 116915290 116952883 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP5C1 509 10 7830092 7849778 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5F1 515 1 111991486 112005395 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATXN7L2 127002 1 110026101 110035426 ataxin 7-like 2
BCAS2 10286 1 115110178 115124260 breast carcinoma amplified sequence 2
BCL2L15 440603 1 114420790 114430169 BCL2-like 15
BEND7 222389 10 13480484 13570974 BEN domain containing 7
BMI1 648 10 22610140 22620413 BMI1 proto-oncogene, polycomb ring finger
BMPR1A 657 10 88516407 88692595 bone morphogenetic protein receptor, type IA
BMPR1B 658 4 95679119 96079599 bone morphogenetic protein receptor, type IB
BTAF1 9044 10 93683526 93790082 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
C10orf11 83938 10 77360998 78319925 chromosome 10 open reading frame 11
C10orf113 387638 10 21414692 21435488 chromosome 10 open reading frame 113
C10orf67 256815 10 23556124 23633774 chromosome 10 open reading frame 67
C10orf99 387695 10 85933494 85945050 chromosome 10 open reading frame 99
C1orf141 400757 1 67557848 67697536 chromosome 1 open reading frame 141
C1orf162 128346 1 112016414 112021134 chromosome 1 open reading frame 162
C1QL3 389941 10 16555742 16564004 complement component 1, q subcomponent-like 3
C4orf29 80167 4 128886461 128960866 chromosome 4 open reading frame 29
C4orf33 132321 4 130014472 130037795 chromosome 4 open reading frame 33
C4orf36 132989 4 87797358 87857354 chromosome 4 open reading frame 36
C5orf49 134121 5 7830491 7851603 chromosome 5 open reading frame 49
C9orf72 203228 9 27546544 27573864 chromosome 9 open reading frame 72
CACNB2 783 10 18429606 18830798 calcium channel, voltage-dependent, beta 2 subunit
CAMK1D 57118 10 12391481 12877545 calcium/calmodulin-dependent protein kinase ID
CCDC3 83643 10 12938627 13141652 coiled-coil domain containing 3
CCT5 22948 5 10250033 10266524 chaperonin containing TCP1, subunit 5 (epsilon)
CD180 4064 5 66478103 66492627 CD180 molecule
CDC123 8872 10 12237964 12292588 cell division cycle 123
CDKN2A 1029 9 21967751 21995300 cyclin-dependent kinase inhibitor 2A
CDKN2B 1030 9 22002902 22009362 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDNF 441549 10 14861249 14880574 cerebral dopamine neurotrophic factor
CDS1 1040 4 85504132 85572491 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CENPK 64105 5 64813593 64858998 centromere protein K
CEP55 55165 10 95256389 95288849 centrosomal protein 55kDa
CH25H 9023 10 90965694 90967071 cholesterol 25-hydroxylase
CMBL 134147 5 10275987 10308138 carboxymethylenebutenolidase homolog (Pseudomonas)
COMMD3 23412 10 22604903 22609235 COMM domain containing 3
COMTD1 118881 10 76993727 76995788 catechol-O-methyltransferase domain containing 1
CPEB3 22849 10 93806449 94050844 cytoplasmic polyadenylation element binding protein 3
CRYZ 1429 1 75171170 75199092 crystallin, zeta (quinone reductase)
CTH 1491 1 70876901 70905534 cystathionine gamma-lyase
CTNNA3 29119 10 67672276 69455927 catenin (cadherin-associated protein), alpha 3
CTNND2 1501 5 10971952 11904155 catenin (cadherin-associated protein), delta 2
CYP26A1 1592 10 94833232 94837647 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26C1 340665 10 94821021 94828454 cytochrome P450, family 26, subfamily C, polypeptide 1
CYP2C18 1562 10 96443251 96495947 cytochrome P450, family 2, subfamily C, polypeptide 18
DAP 1611 5 10679342 10761384 death-associated protein
DEPDC1 55635 1 68939835 68962904 DEP domain containing 1
DIRAS3 9077 1 68511645 68517314 DIRAS family, GTP-binding RAS-like 3
DMP1 1758 4 88571459 88585513 dentin matrix acidic phosphoprotein 1
DMRTA1 63951 9 22446840 22455739 DMRT-like family A1
DMXL1 1657 5 118373467 118584833 Dmx-like 1
DNAJB4 11080 1 78444859 78483648 DnaJ (Hsp40) homolog, subfamily B, member 4
DSPP 1834 4 88529681 88538062 dentin sialophosphoprotein
DTWD2 285605 5 118173017 118324240 DTW domain containing 2
EGR2 1959 10 64571756 64679660 early growth response 2
ELAVL2 1993 9 23690102 23826335 ELAV like neuron-specific RNA binding protein 2
ERBB2IP 55914 5 65222303 65378377 erbb2 interacting protein
FAM13A 10144 4 89647106 90032549 family with sequence similarity 13, member A
FAM159B 100132916 5 63986135 64013917 family with sequence similarity 159, member B
FAM170A 340069 5 118965254 118971517 family with sequence similarity 170, member A
FAM173B 134145 5 10226442 10250009 family with sequence similarity 173, member B
FASTKD3 79072 5 7859272 7869150 FAST kinase domains 3
FAT4 79633 4 126237554 126414087 FAT atypical cadherin 4
FPGT 8790 1 74663896 74699770 fucose-1-phosphate guanylyltransferase
FTMT 94033 5 121187650 121188519 ferritin mitochondrial
FUBP1 8880 1 78409740 78444794 far upstream element (FUSE) binding protein 1
GADD45A 1647 1 68150744 68154021 growth arrest and DNA-damage-inducible, alpha
GIPC2 54810 1 78445226 78604133 GIPC PDZ domain containing family, member 2
GNG12 55970 1 68167149 68299150 guanine nucleotide binding protein (G protein), gamma 12
GPRIN3 285513 4 90157537 90229161 GPRIN family member 3
GRID2 2895 4 93225550 94695707 glutamate receptor, ionotropic, delta 2
HERC3 8916 4 89442199 89629693 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC5 51191 4 89378268 89427314 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 55008 4 89299891 89364263 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HHLA3 11147 1 70820488 70851022 HERV-H LTR-associating 3
HPGDS 27306 4 95219686 95264027 hematopoietic prostaglandin D synthase
HSD17B11 51170 4 88257762 88312538 hydroxysteroid (17-beta) dehydrogenase 11
HSD17B4 3295 5 118788138 118972894 hydroxysteroid (17-beta) dehydrogenase 4
HSPA4L 22824 4 128702976 128761888 heat shock 70kDa protein 4-like
HTR1A 3350 5 63256183 63258334 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IFNA1 3439 9 21440440 21441315 interferon, alpha 1
IFNA10 3446 9 21206180 21207142 interferon, alpha 10
IFNA13 3447 9 21367371 21368075 interferon, alpha 13
IFNA14 3448 9 21239201 21239978 interferon, alpha 14
IFNA16 3449 9 21216372 21217310 interferon, alpha 16
IFNA17 3451 9 21227242 21228221 interferon, alpha 17
IFNA2 3440 9 21384254 21385396 interferon, alpha 2
IFNA21 3452 9 21165636 21166659 interferon, alpha 21
IFNA4 3441 9 21186617 21187598 interferon, alpha 4
IFNA5 3442 9 21304613 21305312 interferon, alpha 5
IFNA6 3443 9 21349834 21351377 interferon, alpha 6
IFNA7 3444 9 21201468 21202204 interferon, alpha 7
IFNA8 3445 9 21409146 21410184 interferon, alpha 8
IFNB1 3456 9 21077104 21077943 interferon, beta 1, fibroblast
IFNE 338376 9 21480841 21482312 interferon, epsilon
IFNK 56832 9 27524312 27526496 interferon, kappa
IFNW1 3467 9 21140631 21142144 interferon, omega 1
IFT74 80173 9 26947037 27062928 intraflagellar transport 74
IL12RB2 3595 1 67773047 67862583 interleukin 12 receptor, beta 2
IL23R 149233 1 67632083 67725662 interleukin 23 receptor
INSL5 10022 1 67263424 67266939 insulin-like 5
INTU 27152 4 128544426 128647892 inturned planar cell polarity protein
IPO11 51194 5 61699799 61924409 importin 11
JMJD1C 221037 10 64926981 65225722 jumonji domain containing 1C
KCNMA1 3778 10 78629359 79398353 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF2A 3796 5 61601989 61833076 kinesin heavy chain member 2A
KLHL9 55958 9 21329670 21335379 kelch-like family member 9
LARP1B 55132 4 128982423 129144086 La ribonucleoprotein domain family, member 1B
LHX8 431707 1 75594119 75627218 LIM homeobox 8
LINGO2 158038 9 27948076 28670283 leucine rich repeat and Ig domain containing 2
LOX 4015 5 121398890 121413980 lysyl oxidase
LRRC19 64922 9 26993134 27005691 leucine rich repeat containing 19
LRRC40 55631 1 70610488 70671303 leucine rich repeat containing 40
LRRC7 57554 1 70034081 70617628 leucine rich repeat containing 7
LRRC70 100130733 5 61874562 61877275 leucine rich repeat containing 70
LRRTM3 347731 10 68685764 68859588 leucine rich repeat transmembrane neuronal 3
MARCH6 10299 5 10353815 10440500 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MAST4 375449 5 65892176 66465423 microtubule associated serine/threonine kinase family member 4
MFSD8 256471 4 128838960 128887150 major facilitator superfamily domain containing 8
MTAP 4507 9 21802542 21931646 methylthioadenosine phosphorylase
MTRR 4552 5 7851299 7906138 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NEXN 91624 1 78354198 78409580 nexilin (F actin binding protein)
NLN 57486 5 65018023 65167553 neurolysin (metallopeptidase M3 family)
NRBF2 29982 10 64893050 64914783 nuclear receptor binding factor 2
NTNG1 22854 1 107682629 108026080 netrin G1
PABPC4L 132430 4 135117488 135122903 poly(A) binding protein, cytoplasmic 4-like
PCDH10 57575 4 134070470 134129356 protocadherin 10
PGRMC2 10424 4 129190397 129209984 progesterone receptor membrane component 2
PLAA 9373 9 26904081 26947461 phospholipase A2-activating protein
PLK4 10733 4 128802016 128820350 polo-like kinase 4
PPWD1 23398 5 64859063 64883376 peptidylprolyl isomerase domain and WD repeat containing 1
PRMT6 55170 1 107599267 107601916 protein arginine methyltransferase 6
PRR16 51334 5 119799973 120023027 proline rich 16
PTGFR 5737 1 78769568 79005434 prostaglandin F receptor (FP)
REEP3 221035 10 65281123 65384883 receptor accessory protein 3
RGS7BP 401190 5 63802084 63908139 regulator of G-protein signaling 7 binding protein
RNF180 285671 5 63461671 63668696 ring finger protein 180
ROPN1L 83853 5 10441636 10472141 rhophilin associated tail protein 1-like
RTKN2 219790 10 63942794 64028466 rhotekin 2
RXFP1 59350 4 159236463 159574524 relaxin/insulin-like family peptide receptor 1
SCLT1 132320 4 129786076 130014764 sodium channel and clathrin linker 1
SEMA5A 9037 5 9035138 9546187 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SFMBT2 57713 10 7200586 7453450 Scm-like with four mbt domains 2
SLC25A31 83447 4 128651533 128695448 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SNCAIP 9627 5 121647049 121799914 synuclein, alpha interacting protein
SRFBP1 153443 5 121297656 121411265 serum response factor binding protein 1
ST6GALNAC5 81849 1 77333126 77531396 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TAS2R1 50834 5 9629109 9712490 taste receptor, type 2, member 1
TEK 7010 9 27109139 27230173 TEK tyrosine kinase, endothelial
TNFAIP8 25816 5 118604387 118735383 tumor necrosis factor, alpha-induced protein 8
TUSC1 286319 9 25676396 25678856 tumor suppressor candidate 1
VDAC2 7417 10 76969912 76991206 voltage-dependent anion channel 2
ZNF365 22891 10 64133951 64431771 zinc finger protein 365
ZNF474 133923 5 121465208 121515312 zinc finger protein 474
ZNF503 84858 10 77157588 77161664 zinc finger protein 503
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Chromothripsis database. 2025 Cai Laboratory