ChromothripsisDB: a curated database of chromothripsis
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	Fusion Gene
	PubMed ID: 23622249	Case ID: PR-08-556	Disease: Prostate cancer	Genome Assembly: GRCh37/hg19
Gene Symbol 1 Chromosome1 Description 1 Gene Symbol 2 Chromosome2 Description 2 ABCA13 7 ATP-binding cassette, sub-family A (ABC1), member 13 FIGNL1 7 fidgetin-like 1 AMPH 7 amphiphysin VPS41 7 vacuolar protein sorting 41 homolog (S. cerevisiae) AQR 15 aquarius intron-binding spliceosomal factor INO80 15 INO80 complex subunit ARID1B 6 AT rich interactive domain 1B (SWI1-like) ZDHHC14 6 zinc finger, DHHC-type containing 14 BRD8 5 bromodomain containing 8 HARS 5 histidyl-tRNA synthetase CCDC18 1 coiled-coil domain containing 18 GCLM 1 glutamate-cysteine ligase, modifier subunit CDH2 18 cadherin 2, type 1, N-cadherin (neuronal) TTC28 22 tetratricopeptide repeat domain 28 CDS1 4 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 ARHGAP24 4 Rho GTPase activating protein 24 CELF4 18 CUGBP, Elav-like family member 4 PIK3C3 18 phosphatidylinositol 3-kinase, catalytic subunit type 3 CHL1 3 cell adhesion molecule L1-like CNTN6 3 contactin 6 CNBD1 8 cyclic nucleotide binding domain containing 1 MMP16 8 matrix metallopeptidase 16 (membrane-inserted) CYB5R4 6 cytochrome b5 reductase 4 TBX18 6 T-box 18 DDX10 11 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 SKA3 13 spindle and kinetochore associated complex subunit 3 DOK6 18 docking protein 6 NETO1 18 neuropilin (NRP) and tolloid (TLL)-like 1 DOPEY2 21 dopey family member 2 DYRK1A 21 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A DPY19L1 7 dpy-19-like 1 (C. elegans) POU6F2 7 POU class 6 homeobox 2 EEPD1 7 endonuclease/exonuclease/phosphatase family domain containing 1 ELMO1 7 engulfment and cell motility 1 EEPD1 7 endonuclease/exonuclease/phosphatase family domain containing 1 POU6F2 7 POU class 6 homeobox 2 EXOC3 5 exocyst complex component 3 CEP72 5 centrosomal protein 72kDa EYS 6 eyes shut homolog (Drosophila) ARID1B 6 AT rich interactive domain 1B (SWI1-like) EYS 6 eyes shut homolog (Drosophila) SYNE1 6 spectrin repeat containing, nuclear envelope 1 FNBP1L 1 formin binding protein 1-like BCAR3 1 breast cancer anti-estrogen resistance 3 GHR 5 growth hormone receptor PRKD1 14 protein kinase D1 GLRA3 4 glycine receptor, alpha 3 WDR17 4 WD repeat domain 17 GRIN2B 12 glutamate receptor, ionotropic, N-methyl D-aspartate 2B PIK3C2G 12 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma HECW1 7 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 ABCA13 7 ATP-binding cassette, sub-family A (ABC1), member 13 HERPUD2 7 HERPUD family member 2 POU6F2 7 POU class 6 homeobox 2 KCND2 7 potassium channel, voltage gated Shal related subfamily D, member 2 SPTLC3 20 serine palmitoyltransferase, long chain base subunit 3 KCNJ6 21 potassium channel, inwardly rectifying subfamily J, member 6 DSCR4 21 Down syndrome critical region 4 KDM4C 9 lysine (K)-specific demethylase 4C PTPRD 9 protein tyrosine phosphatase, receptor type, D KIAA0895 7 KIAA0895 AMPH 7 amphiphysin KIAA0895 7 KIAA0895 POU6F2 7 POU class 6 homeobox 2 KIAA1328 18 KIAA1328 RIT2 18 Ras-like without CAAX 2 MLANA 9 melan-A KDM4C 9 lysine (K)-specific demethylase 4C MYL1 2 myosin, light chain 1, alkali; skeletal, fast CPS1 2 carbamoyl-phosphate synthase 1, mitochondrial NCAM1 11 neural cell adhesion molecule 1 USP28 11 ubiquitin specific peptidase 28 PLXNC1 12 plexin C1 NTN4 12 netrin 4 PRIM2 6 primase, DNA, polypeptide 2 (58kDa) EYS 6 eyes shut homolog (Drosophila) PRSS3 9 protease, serine, 3 UBE2R2 9 ubiquitin-conjugating enzyme E2R 2 PTPRD 9 protein tyrosine phosphatase, receptor type, D NFIB 9 nuclear factor I/B RFTN1 3 raftlin, lipid raft linker 1 CADM2 3 cell adhesion molecule 2 RFX3 9 regulatory factor X, 3 (influences HLA class II expression) IL33 9 interleukin 33 RFX3 9 regulatory factor X, 3 (influences HLA class II expression) INSL6 9 insulin-like 6 RIC3 11 RIC3 acetylcholine receptor chaperone TRIM66 11 tripartite motif containing 66 RIT2 18 Ras-like without CAAX 2 ZNF407 18 zinc finger protein 407 SLC23A2 20 solute carrier family 23 (ascorbic acid transporter), member 2 SPTLC3 20 serine palmitoyltransferase, long chain base subunit 3 TBC1D5 3 TBC1 domain family, member 5 CADM2 3 cell adhesion molecule 2 WDFY3 4 WD repeat and FYVE domain containing 3 ARHGAP24 4 Rho GTPase activating protein 24

	Affected Gene
	PubMed ID: 23622249	Case ID: PR-08-556	Disease: Prostate cancer	Genome Assembly: GRCh37/hg19
Gene Symbol Entrez Gene Chromosome Start End Description A1CF 29974 10 52559169 52645435 APOBEC1 complementation factor ABCA13 154664 7 48211055 48687092 ATP-binding cassette, sub-family A (ABC1), member 13 ABLIM1 3983 10 116190872 116444762 actin binding LIM protein 1 ACO1 48 9 32384618 32454767 aconitase 1, soluble ADCY8 114 8 131792547 132054672 adenylate cyclase 8 (brain) AFF2 2334 X 148500619 149000663 AF4/FMR2 family, member 2 AMPH 273 7 38423305 38671167 amphiphysin ANAPC1 64682 2 112523848 112642267 anaphase promoting complex subunit 1 ANKRD33B 651746 5 10564442 10650308 ankyrin repeat domain 33B AQR 9716 15 35147732 35262040 aquarius intron-binding spliceosomal factor ARFIP1 27236 4 153701089 153839615 ADP-ribosylation factor interacting protein 1 ARHGAP24 83478 4 86396267 86923823 Rho GTPase activating protein 24 ARID1B 57492 6 157099063 157531913 AT rich interactive domain 1B (SWI1-like) BCAR3 8412 1 94027347 94312706 breast cancer anti-estrogen resistance 3 BRD8 10902 5 137475455 137514675 bromodomain containing 8 BTBD3 22903 20 11871371 11907257 BTB (POZ) domain containing 3 C14orf28 122525 14 45366498 45376460 chromosome 14 open reading frame 28 C2orf88 84281 2 190744335 191068210 chromosome 2 open reading frame 88 CADM2 253559 3 85008132 86123579 cell adhesion molecule 2 CAMK4 814 5 110559351 110830584 calcium/calmodulin-dependent protein kinase IV CCDC102B 79839 18 66382446 66722426 coiled-coil domain containing 102B CCDC18 343099 1 93645476 93744287 coiled-coil domain containing 18 CCDC85A 114800 2 56411258 56613308 coiled-coil domain containing 85A CCDC92 80212 12 124403207 124457378 coiled-coil domain containing 92 CD226 10666 18 67498394 67629039 CD226 molecule CD274 29126 9 5450503 5470566 CD274 molecule CDC73 79577 1 193091147 193223031 cell division cycle 73 CDH2 1000 18 25530930 25757410 cadherin 2, type 1, N-cadherin (neuronal) CDK13 8621 7 39989636 40136733 cyclin-dependent kinase 13 CDS1 1040 4 85504132 85572491 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 CELF2 10659 10 11047259 11378674 CUGBP, Elav-like family member 2 CELF4 56853 18 34823010 35146000 CUGBP, Elav-like family member 4 CEP72 55722 5 612387 667283 centrosomal protein 72kDa CHL1 10752 3 238279 451090 cell adhesion molecule L1-like CNBD1 168975 8 87878670 88627447 cyclic nucleotide binding domain containing 1 CNKSR3 154043 6 154708638 154831793 CNKSR family member 3 CNTN6 27255 3 1134260 1445901 contactin 6 CNTNAP2 26047 7 145813453 148118090 contactin associated protein-like 2 CNTNAP5 129684 2 124782864 125672864 contactin associated protein-like 5 COL25A1 84570 4 109731877 110223813 collagen, type XXV, alpha 1 CPS1 1373 2 211342406 211543831 carbamoyl-phosphate synthase 1, mitochondrial CSMD3 114788 8 113235157 114449328 CUB and Sushi multiple domains 3 CUL4A 8451 13 113862552 113919399 cullin 4A CYB5R4 51167 6 84569362 84677143 cytochrome b5 reductase 4 DACH2 117154 X 86148451 86832602 dachshund family transcription factor 2 DBX2 440097 12 45408455 45444882 developing brain homeobox 2 DDX10 1662 11 108535752 108811657 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 DENND1A 57706 9 126141933 126692431 DENN/MADD domain containing 1A DOK6 220164 18 67068291 67516323 docking protein 6 DOPEY2 9980 21 37529080 37666572 dopey family member 2 DPP10 57628 2 115199876 116603328 dipeptidyl-peptidase 10 (non-functional) DPY19L1 23333 7 34968488 35077883 dpy-19-like 1 (C. elegans) DSCR4 10281 21 39323728 39493454 Down syndrome critical region 4 DTNB 1838 2 25600067 25896503 dystrobrevin, beta DYNC2H1 79659 11 102980160 103350591 dynein, cytoplasmic 2, heavy chain 1 DYRK1A 1859 21 38738092 38889753 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A EDIL3 10085 5 83236373 83680611 EGF-like repeats and discoidin I-like domains 3 EEPD1 80820 7 36192758 36341152 endonuclease/exonuclease/phosphatase family domain containing 1 EFNA5 1946 5 106712590 107006596 ephrin-A5 ELMO1 9844 7 36893961 37488852 engulfment and cell motility 1 EPHA5 2044 4 66185281 66536213 EPH receptor A5 EPHA6 285220 3 96533425 97471304 EPH receptor A6 EXOC3 11336 5 443273 472052 exocyst complex component 3 EYS 346007 6 64429876 66417118 eyes shut homolog (Drosophila) FAM171B 165215 2 187558698 187630685 family with sequence similarity 171, member B FAM179B 23116 14 45431411 45543634 family with sequence similarity 179, member B FBXO8 26269 4 175157809 175205415 F-box protein 8 FCGRT 2217 19 50010073 50029590 Fc fragment of IgG, receptor, transporter, alpha FER 2241 5 108083523 108532542 fer (fps/fes related) tyrosine kinase FIGNL1 63979 7 50511831 50518088 fidgetin-like 1 FNBP1L 54874 1 93913688 94020218 formin binding protein 1-like FOXP2 93986 7 113726382 114333827 forkhead box P2 FSTL5 56884 4 162305049 163085187 follistatin-like 5 GAD2 2572 10 26505236 26593487 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) GALNT13 114805 2 154728426 155310361 polypeptide N-acetylgalactosaminyltransferase 13 GALNTL6 442117 4 172733405 173962710 polypeptide N-acetylgalactosaminyltransferase-like 6 GBE1 2632 3 81538850 81811312 glucan (1,4-alpha-), branching enzyme 1 GCLM 2730 1 94350761 94374966 glutamate-cysteine ligase, modifier subunit GFM1 85476 3 158362067 158410364 G elongation factor, mitochondrial 1 GFRA1 2674 10 117816444 118032979 GDNF family receptor alpha 1 GHR 2690 5 42423879 42721979 growth hormone receptor GLRA3 8001 4 175558065 175750465 glycine receptor, alpha 3 GPR141 353345 7 37723399 37873390 G protein-coupled receptor 141 GPR63 81491 6 97242002 97285353 G protein-coupled receptor 63 GRIA4 2893 11 105480721 105852819 glutamate receptor, ionotropic, AMPA 4 GRIN2B 2904 12 13693165 14133053 glutamate receptor, ionotropic, N-methyl D-aspartate 2B HARS 3035 5 140052758 140071609 histidyl-tRNA synthetase HECW1 23072 7 43152198 43605600 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 HERPUD2 64224 7 35672269 35735181 HERPUD family member 2 HS3ST4 9951 16 25703347 26149009 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 IBTK 25998 6 82879700 82957471 inhibitor of Bruton agammaglobulinemia tyrosine kinase IKZF1 10320 7 50343720 50472799 IKAROS family zinc finger 1 (Ikaros) IL15 3600 4 142557752 142655140 interleukin 15 IL33 90865 9 6215805 6257983 interleukin 33 INO80 54617 15 41271078 41408552 INO80 complex subunit INSL6 11172 9 5131979 5185668 insulin-like 6 ITPR1 3708 3 4535032 4889524 inositol 1,4,5-trisphosphate receptor, type 1 JAK2 3717 9 4985033 5128183 Janus kinase 2 KANK1 23189 9 470291 746105 KN motif and ankyrin repeat domains 1 KCND2 3751 7 119913722 120390385 potassium channel, voltage gated Shal related subfamily D, member 2 KCNH8 131096 3 19189946 19577138 potassium channel, voltage gated eag related subfamily H, member 8 KCNIP1 30820 5 169780491 170163636 Kv channel interacting protein 1 KCNJ6 3763 21 38979678 39288749 potassium channel, inwardly rectifying subfamily J, member 6 KDM4C 23081 9 6720863 7175648 lysine (K)-specific demethylase 4C KIAA0895 23366 7 36363830 36429734 KIAA0895 KIAA1328 57536 18 34409069 34812135 KIAA1328 KIAA2026 158358 9 5881596 6007901 KIAA2026 KIF16B 55614 20 16252749 16554078 kinesin family member 16B KIF21A 55605 12 39687030 39837192 kinesin family member 21A KLHL29 114818 2 23608088 23931481 kelch-like family member 29 KLRG1 10219 12 9102640 9163356 killer cell lectin-like receptor subfamily G, member 1 LAMA3 3909 18 21269407 21535030 laminin, alpha 3 LCORL 254251 4 17842822 18023499 ligand dependent nuclear receptor corepressor-like LPXN 9404 11 58294344 58345693 leupaxin MBP 4155 18 74690783 74845639 myelin basic protein MCC 4163 5 112357796 112824527 mutated in colorectal cancers MIR510 574515 X 147272335 147272408 microRNA 510 MLANA 2315 9 5890802 5910606 melan-A MMP16 4325 8 89044237 89340254 matrix metallopeptidase 16 (membrane-inserted) MTIF2 4528 2 55463731 55496483 mitochondrial translational initiation factor 2 MTR 4548 1 236958610 237067281 5-methyltetrahydrofolate-homocysteine methyltransferase MYL1 4632 2 211154874 211179914 myosin, light chain 1, alkali; skeletal, fast NCAM1 4684 11 112831997 113149158 neural cell adhesion molecule 1 NETO1 81832 18 70409549 70535381 neuropilin (NRP) and tolloid (TLL)-like 1 NFIB 4781 9 14081842 14398982 nuclear factor I/B NHSL2 340527 X 71911073 72153286 NHS-like 2 NKAIN3 286183 8 63161150 63912211 Na+/K+ transporting ATPase interacting 3 NKD2 85409 5 1008944 1039058 naked cuticle homolog 2 (Drosophila) NMD3 51068 3 160822484 160971320 NMD3 ribosome export adaptor NRAP 4892 10 115348475 115423886 nebulin-related anchoring protein NRG3 10718 10 83635070 84746935 neuregulin 3 NTN4 59277 12 96051583 96184930 netrin 4 NUDT21 11051 16 56463045 56486111 nudix (nucleoside diphosphate linked moiety X)-type motif 21 OGFOD1 55239 16 56485402 56513012 2-oxoglutarate and iron-dependent oxygenase domain containing 1 OPRM1 4988 6 154331631 154568001 opioid receptor, mu 1 OSTN 344901 3 190917030 190983404 osteocrin PARK2 5071 6 161768452 163148803 parkin RBR E3 ubiquitin protein ligase PCDH11Y 83259 Y 5000226 5742228 protocadherin 11 Y-linked PDE6A 5145 5 149237519 149324356 phosphodiesterase 6A, cGMP-specific, rod, alpha PIGN 23556 18 59710800 59854351 phosphatidylinositol glycan anchor biosynthesis, class N PIK3C2G 5288 12 18400548 18801348 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma PIK3C3 5289 18 39535171 39667794 phosphatidylinositol 3-kinase, catalytic subunit type 3 PKD1L1 168507 7 47814250 47988088 polycystic kidney disease 1 like 1 PKHD1 5314 6 51480098 51952423 polycystic kidney and hepatic disease 1 (autosomal recessive) PLSCR5 389158 3 146294342 146324003 phospholipid scramblase family, member 5 PLXNC1 10154 12 94542499 94701451 plexin C1 POT1 25913 7 124462440 124570037 protection of telomeres 1 POU6F2 11281 7 39017598 39532694 POU class 6 homeobox 2 PRIM2 5558 6 57179603 57513375 primase, DNA, polypeptide 2 (58kDa) PRKD1 5587 14 30045687 30661104 protein kinase D1 PRKG1 5592 10 52750945 54058110 protein kinase, cGMP-dependent, type I PRSS3 5646 9 33750515 33799230 protease, serine, 3 PTPRD 5789 9 8314246 10612723 protein tyrosine phosphatase, receptor type, D RB1 5925 13 48877887 49056122 retinoblastoma 1 RBL2 5934 16 53467889 53525561 retinoblastoma-like 2 RELL2 285613 5 141016517 141020644 RELT-like 2 RFTN1 23180 3 16355081 16555533 raftlin, lipid raft linker 1 RFX3 5991 9 3218297 3526004 regulatory factor X, 3 (influences HLA class II expression) RIC3 79608 11 8127597 8190602 RIC3 acetylcholine receptor chaperone RIT2 6014 18 40323192 40695657 Ras-like without CAAX 2 ROBO1 6091 3 78646390 79816965 roundabout, axon guidance receptor, homolog 1 (Drosophila) RPRD2 23248 1 150335567 150449042 regulation of nuclear pre-mRNA domain containing 2 RPS6KA2 6196 6 166822852 167319939 ribosomal protein S6 kinase, 90kDa, polypeptide 2 RSPO3 84870 6 127439749 127518910 R-spondin 3 RYR3 6263 15 33603163 34158303 ryanodine receptor 3 SAMD12 401474 8 119201698 119634234 sterile alpha motif domain containing 12 SCN9A 6335 2 167051695 167232503 sodium channel, voltage gated, type IX alpha subunit SEMA5A 9037 5 9035138 9546187 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A SKA3 221150 13 21727734 21750741 spindle and kinetochore associated complex subunit 3 SLC1A1 6505 9 4490444 4587469 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 SLC23A2 9962 20 4833002 4990939 solute carrier family 23 (ascorbic acid transporter), member 2 SLC2A13 114134 12 40148823 40499891 solute carrier family 2 (facilitated glucose transporter), member 13 SLC30A8 169026 8 117962512 118188953 solute carrier family 30 (zinc transporter), member 8 SLC39A12 221074 10 18240768 18332221 solute carrier family 39 (zinc transporter), member 12 SLCO3A1 28232 15 92396925 92715665 solute carrier organic anion transporter family, member 3A1 SLITRK3 22865 3 164904508 164914897 SLIT and NTRK-like family, member 3 SND1 27044 7 127292234 127732661 staphylococcal nuclease and tudor domain containing 1 SORCS1 114815 10 108333421 108924292 sortilin-related VPS10 domain containing receptor 1 SPTLC3 55304 20 12989627 13147411 serine palmitoyltransferase, long chain base subunit 3 STXBP6 29091 14 25278862 25519503 syntaxin binding protein 6 (amisyn) SYNE1 23345 6 152442819 152958936 spectrin repeat containing, nuclear envelope 1 SYT4 6860 18 40847843 40857615 synaptotagmin IV TASP1 55617 20 13246709 13619587 taspase, threonine aspartase, 1 TBC1D5 9779 3 17198654 18486309 TBC1 domain family, member 5 TBX18 9096 6 85397069 85474237 T-box 18 TBX20 57057 7 35242042 35293758 T-box 20 THSD7B 80731 2 137523115 138435287 thrombospondin, type I, domain containing 7B TMCO5A 145942 15 38214140 38259925 transmembrane and coiled-coil domains 5A TNIK 23043 3 170779128 171178197 TRAF2 and NCK interacting kinase TNPO3 23534 7 128594948 128695198 transportin 3 TNS3 64759 7 47314752 47622156 tensin 3 TPR 7175 1 186280784 186344825 translocated promoter region, nuclear basket protein TRDN 10345 6 123537483 123958238 triadin TRIM66 9866 11 8633584 8693413 tripartite motif containing 66 TRPM3 80036 9 73143979 74061820 transient receptor potential cation channel, subfamily M, member 3 TSHZ1 10194 18 72922710 73001905 teashirt zinc finger homeobox 1 TTC28 23331 22 28374004 29075853 tetratricopeptide repeat domain 28 TTTY10 246119 Y 20465668 20519228 testis-specific transcript, Y-linked 10 (non-protein coding) UBE2R2 54926 9 33817565 33920402 ubiquitin-conjugating enzyme E2R 2 UHRF2 115426 9 6413151 6507054 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase USP28 57646 11 113668596 113746292 ubiquitin specific peptidase 28 VPS41 27072 7 38762563 38971994 vacuolar protein sorting 41 homolog (S. cerevisiae) WDFY3 23001 4 85590704 85887544 WD repeat and FYVE domain containing 3 WDR17 116966 4 176986985 177103978 WD repeat domain 17 ZBBX 79740 3 166958075 167099134 zinc finger, B-box domain containing ZDHHC14 79683 6 157802165 158099178 zinc finger, DHHC-type containing 14 ZNF407 55628 18 72265106 72777627 zinc finger protein 407 ZNF804A 91752 2 185463093 185804219 zinc finger protein 804A top

Chromothripsis database. 2025 Cai Laboratory