ChromothripsisDB: a curated database of chromothripsis
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	Fusion Gene
	PubMed ID: 23622249	Case ID: PR-4240	Disease: Prostate cancer	Genome Assembly: GRCh37/hg19
Gene Symbol 1 Chromosome1 Description 1 Gene Symbol 2 Chromosome2 Description 2 ACADL 2 acyl-CoA dehydrogenase, long chain UTRN 6 utrophin ACSS2 20 acyl-CoA synthetase short-chain family member 2 MYH7B 20 myosin, heavy chain 7B, cardiac muscle, beta ADCY3 2 adenylate cyclase 3 ENOX1 13 ecto-NOX disulfide-thiol exchanger 1 AGBL4 1 ATP/GTP binding protein-like 4 CD58 1 CD58 molecule AGBL4 1 ATP/GTP binding protein-like 4 GRK5 10 G protein-coupled receptor kinase 5 AGBL4 1 ATP/GTP binding protein-like 4 LHPP 10 phospholysine phosphohistidine inorganic pyrophosphate phosphatase AGBL4 1 ATP/GTP binding protein-like 4 RGS10 10 regulator of G-protein signaling 10 AKAP6 14 A kinase (PRKA) anchor protein 6 NPAS3 14 neuronal PAS domain protein 3 ANKRD46 8 ankyrin repeat domain 46 NDRG1 8 N-myc downstream regulated 1 ARCN1 11 archain 1 PHLDB1 11 pleckstrin homology-like domain, family B, member 1 BLMH 17 bleomycin hydrolase AP2B1 17 adaptor-related protein complex 2, beta 1 subunit BLMH 17 bleomycin hydrolase LIG3 17 ligase III, DNA, ATP-dependent C9orf47 9 chromosome 9 open reading frame 47 S1PR3 9 sphingosine-1-phosphate receptor 3 CCDC73 11 coiled-coil domain containing 73 BCKDHA 19 branched chain keto acid dehydrogenase E1, alpha polypeptide CPD 17 carboxypeptidase D AP2B1 17 adaptor-related protein complex 2, beta 1 subunit EFCAB5 17 EF-hand calcium binding domain 5 PEX12 17 peroxisomal biogenesis factor 12 FAM178A 10 family with sequence similarity 178, member A SEMA4G 10 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G FGGY 1 FGGY carbohydrate kinase domain containing MKLN1 7 muskelin 1, intracellular mediator containing kelch motifs FN1 2 fibronectin 1 ACLY 17 ATP citrate lyase FN1 2 fibronectin 1 KLHL11 17 kelch-like family member 11 GNB2L1 5 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 EEA1 12 early endosome antigen 1 ICK 6 intestinal cell (MAK-like) kinase TMPRSS15 21 transmembrane protease, serine 15 LPP 3 LIM domain containing preferred translocation partner in lipoma COG5 7 component of oligomeric golgi complex 5 NAA25 12 N(alpha)-acetyltransferase 25, NatB auxiliary subunit TRAFD1 12 TRAF-type zinc finger domain containing 1 NOP2 12 NOP2 nucleolar protein CHD4 12 chromodomain helicase DNA binding protein 4 NPAS3 14 neuronal PAS domain protein 3 WIPF2 17 WAS/WASL interacting protein family, member 2 NRF1 7 nuclear respiratory factor 1 BRAF 7 B-Raf proto-oncogene, serine/threonine kinase NUP88 17 nucleoporin 88kDa C1QBP 17 complement component 1, q subcomponent binding protein PHACTR1 6 phosphatase and actin regulator 1 SEMA3E 7 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E PRKCB 16 protein kinase C, beta HUWE1 X HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase RASL10B 17 RAS-like, family 10, member B WIPF2 17 WAS/WASL interacting protein family, member 2 RAVER2 1 ribonucleoprotein, PTB-binding 2 MECOM 3 MDS1 and EVI1 complex locus SGMS2 4 sphingomyelin synthase 2 SPDEF 6 SAM pointed domain containing ETS transcription factor SLC25A16 10 solute carrier family 25 (mitochondrial carrier), member 16 TET1 10 tet methylcytosine dioxygenase 1 SLC4A11 20 solute carrier family 4, sodium borate transporter, member 11 C20orf194 20 chromosome 20 open reading frame 194 STAT2 12 signal transducer and activator of transcription 2, 113kDa APOF 12 apolipoprotein F SYNRG 17 synergin, gamma KRT9 17 keratin 9, type I TBC1D10B 16 TBC1 domain family, member 10B MYLPF 16 myosin light chain, phosphorylatable, fast skeletal muscle THRB 3 thyroid hormone receptor, beta SH3PXD2B 5 SH3 and PX domains 2B TMED3 15 transmembrane emp24 protein transport domain containing 3 AATF 17 apoptosis antagonizing transcription factor VKORC1L1 7 vitamin K epoxide reductase complex, subunit 1-like 1 KIAA0586 14 KIAA0586 ZNF516 18 zinc finger protein 516 MBP 18 myelin basic protein

	Affected Gene
	PubMed ID: 23622249	Case ID: PR-4240	Disease: Prostate cancer	Genome Assembly: GRCh37/hg19
Gene Symbol Entrez Gene Chromosome Start End Description AATF 26574 17 35306175 35414171 apoptosis antagonizing transcription factor ACADL 33 2 211052663 211090215 acyl-CoA dehydrogenase, long chain ACLY 47 17 40023161 40086795 ATP citrate lyase ACSS2 55902 20 33459949 33515769 acyl-CoA synthetase short-chain family member 2 ADAM23 8745 2 207308263 207485851 ADAM metallopeptidase domain 23 ADAMTS3 9508 4 73146686 73434516 ADAM metallopeptidase with thrombospondin type 1 motif, 3 ADAMTS6 11174 5 64444563 64777747 ADAM metallopeptidase with thrombospondin type 1 motif, 6 ADCY3 109 2 25042038 25142708 adenylate cyclase 3 AGBL4 84871 1 48998527 50489585 ATP/GTP binding protein-like 4 AGT 183 1 230838269 230850043 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) AKAP6 9472 14 32798479 33300567 A kinase (PRKA) anchor protein 6 AMFR 267 16 56395364 56459450 autocrine motility factor receptor, E3 ubiquitin protein ligase ANKRD18A 253650 9 38540566 38620657 ankyrin repeat domain 18A ANKRD46 157567 8 101521980 101572012 ankyrin repeat domain 46 AP2B1 163 17 33905065 34053436 adaptor-related protein complex 2, beta 1 subunit APOF 319 12 56754353 56756607 apolipoprotein F ARCN1 372 11 118443105 118473748 archain 1 ATAD2 29028 8 124332090 124428590 ATPase family, AAA domain containing 2 ATF6 22926 1 161736084 161933860 activating transcription factor 6 ATXN1 6310 6 16299343 16761722 ataxin 1 ATXN10 25814 22 46067678 46241187 ataxin 10 AUTS2 26053 7 69063905 70258054 autism susceptibility candidate 2 BAZ1A 11177 14 35221937 35344853 bromodomain adjacent to zinc finger domain, 1A BBS9 27241 7 33168856 33645680 Bardet-Biedl syndrome 9 BCKDHA 593 19 41884215 41930910 branched chain keto acid dehydrogenase E1, alpha polypeptide BCL2 596 18 60790579 60987361 B-cell CLL/lymphoma 2 BLMH 642 17 28575218 28619074 bleomycin hydrolase BRAF 673 7 140419127 140624564 B-Raf proto-oncogene, serine/threonine kinase C12orf42 374470 12 103631369 103889749 chromosome 12 open reading frame 42 C1QBP 708 17 5336097 5352150 complement component 1, q subcomponent binding protein C20orf194 25943 20 3229951 3388272 chromosome 20 open reading frame 194 C9orf171 389799 9 135285430 135448704 chromosome 9 open reading frame 171 C9orf47 286223 9 91605778 91611055 chromosome 9 open reading frame 47 CCDC73 493860 11 32623792 32816204 coiled-coil domain containing 73 CD58 965 1 117057157 117113661 CD58 molecule CHD1L 9557 1 146714291 146767443 chromodomain helicase DNA binding protein 1-like CHD4 1108 12 6679249 6716642 chromodomain helicase DNA binding protein 4 CLN3 1201 16 28477974 28503333 ceroid-lipofuscinosis, neuronal 3 CLTA 1211 9 36190853 36304778 clathrin, light chain A COG5 10466 7 106842000 107204959 component of oligomeric golgi complex 5 CPD 1362 17 28705923 28797007 carboxypeptidase D CRTC3 64784 15 91073157 91188577 CREB regulated transcription coactivator 3 CTNNA3 29119 10 67672276 69455927 catenin (cadherin-associated protein), alpha 3 CWC27 10283 5 64064757 64314590 CWC27 spliceosome-associated protein homolog (S. cerevisiae) DISC1 27185 1 231762561 232177018 disrupted in schizophrenia 1 DNAH14 127602 1 225083964 225586996 dynein, axonemal, heavy chain 14 DNAH3 55567 16 20944433 21170762 dynein, axonemal, heavy chain 3 EDARADD 128178 1 236511562 236648214 EDAR-associated death domain EEA1 8411 12 93164413 93323107 early endosome antigen 1 EFCAB5 374786 17 28256218 28435470 EF-hand calcium binding domain 5 EHBP1L1 254102 11 65343509 65360121 EH domain binding protein 1-like 1 ENOX1 55068 13 43787654 44361044 ecto-NOX disulfide-thiol exchanger 1 EPB41L4B 54566 9 111934255 112083244 erythrocyte membrane protein band 4.1 like 4B EXTL3 2137 8 28457986 28613116 exostosin-like glycosyltransferase 3 FAM178A 55719 10 102672326 102724893 family with sequence similarity 178, member A FAM179B 23116 14 45431411 45543634 family with sequence similarity 179, member B FAM188B 84182 7 30811033 30932002 family with sequence similarity 188, member B FBXW2 26190 9 123514256 123555690 F-box and WD repeat domain containing 2 FGGY 55277 1 59762310 60233347 FGGY carbohydrate kinase domain containing FN1 2335 2 216225163 216300895 fibronectin 1 FOXA1 3169 14 38059189 38069245 forkhead box A1 FREM2 341640 13 39261266 39460074 FRAS1 related extracellular matrix protein 2 FRMD6 122786 14 51955818 52197445 FERM domain containing 6 FSTL4 23105 5 132532147 132948255 follistatin-like 4 GALNT10 55568 5 153570290 153800544 polypeptide N-acetylgalactosaminyltransferase 10 GMPPB 29925 3 49754277 49761384 GDP-mannose pyrophosphorylase B GNB2L1 10399 5 180663909 180675096 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 GRIA4 2893 11 105480721 105852819 glutamate receptor, ionotropic, AMPA 4 GRK5 2869 10 120967101 121215131 G protein-coupled receptor kinase 5 GRXCR1 389207 4 42895284 43032675 glutaredoxin, cysteine rich 1 GUCY1B3 2983 4 156680144 156728743 guanylate cyclase 1, soluble, beta 3 HGSNAT 138050 8 42995556 43057998 heparan-alpha-glucosaminide N-acetyltransferase HMGCLL1 54511 6 55299167 55444012 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 HPCAL1 3241 2 10443015 10567743 hippocalcin-like 1 HUWE1 10075 X 53532096 53686729 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase ICK 22858 6 52866077 52926600 intestinal cell (MAK-like) kinase IFT80 57560 3 159974774 160117668 intraflagellar transport 80 IL1RAPL1 11141 X 28587564 29956350 interleukin 1 receptor accessory protein-like 1 KBTBD2 25948 7 32907784 32933743 kelch repeat and BTB (POZ) domain containing 2 KCNAB1 7881 3 155755490 156256545 potassium channel, voltage gated subfamily A regulatory beta subunit 1 KCTD20 222658 6 36410544 36458920 potassium channel tetramerization domain containing 20 KDM4C 23081 9 6720863 7175648 lysine (K)-specific demethylase 4C KIAA0586 9786 14 58894103 59015216 KIAA0586 KIAA1549 57670 7 138516126 138666064 KIAA1549 KLHL11 55175 17 40009797 40021684 kelch-like family member 11 KRT9 3857 17 39722096 39728310 keratin 9, type I LHPP 64077 10 126150403 126306457 phospholysine phosphohistidine inorganic pyrophosphate phosphatase LIG3 3980 17 33307513 33332083 ligase III, DNA, ATP-dependent LPP 4026 3 187871072 188608460 LIM domain containing preferred translocation partner in lipoma LRCH3 84859 3 197518097 197615307 leucine-rich repeats and calponin homology (CH) domain containing 3 LYPLAL1 127018 1 219347186 219386207 lysophospholipase-like 1 MARK1 4139 1 220701568 220837803 MAP/microtubule affinity-regulating kinase 1 MBP 4155 18 74690783 74845639 myelin basic protein ME3 10873 11 86152150 86383678 malic enzyme 3, NADP(+)-dependent, mitochondrial MECOM 2122 3 168801287 169381406 MDS1 and EVI1 complex locus MICAL2 9645 11 12115543 12285334 microtubule associated monooxygenase, calponin and LIM domain containing 2 MKLN1 4289 7 130794855 131181395 muskelin 1, intracellular mediator containing kelch motifs MTHFD1L 25902 6 151186685 151423023 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like MYH7B 57644 20 33563206 33590240 myosin, heavy chain 7B, cardiac muscle, beta MYLPF 29895 16 30382255 30389312 myosin light chain, phosphorylatable, fast skeletal muscle NAA25 80018 12 112464500 112546826 N(alpha)-acetyltransferase 25, NatB auxiliary subunit NBPF10 100132406 1 145289772 145370303 neuroblastoma breakpoint family, member 10 NBR1 4077 17 41322498 41363708 neighbor of BRCA1 gene 1 NCKAP5 344148 2 133429374 134326034 NCK-associated protein 5 NCOA3 8202 20 46130601 46285621 nuclear receptor coactivator 3 NDRG1 10397 8 134249414 134314265 N-myc downstream regulated 1 NDST3 9348 4 118954773 119179803 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 NEO1 4756 15 73344051 73597547 neogenin 1 NME7 29922 1 169101769 169337205 NME/NM23 family member 7 NOP2 4839 12 6666029 6677857 NOP2 nucleolar protein NPAS3 64067 14 33404139 34273382 neuronal PAS domain protein 3 NRF1 4899 7 129251555 129396922 nuclear respiratory factor 1 NRK 203447 X 105821856 105958612 Nik related kinase NTM 50863 11 131240373 132206716 neurotrimin NUP88 4927 17 5264258 5323480 nucleoporin 88kDa NVL 4931 1 224415036 224518089 nuclear VCP-like OPHN1 4983 X 68042344 68433841 oligophrenin 1 PAK1 5058 11 77032752 77185680 p21 protein (Cdc42/Rac)-activated kinase 1 PCDH15 65217 10 55562531 57387702 protocadherin-related 15 PDE11A 50940 2 178487980 178973066 phosphodiesterase 11A PDE4DIP 9659 1 144836157 145076186 phosphodiesterase 4D interacting protein PEX12 5193 17 33901814 33905882 peroxisomal biogenesis factor 12 PHACTR1 221692 6 12717893 13288645 phosphatase and actin regulator 1 PHLDB1 23187 11 118477155 118528741 pleckstrin homology-like domain, family B, member 1 PPM1D 8493 17 58677544 58741849 protein phosphatase, Mg2+/Mn2+ dependent, 1D PRIM2 5558 6 57179603 57513375 primase, DNA, polypeptide 2 (58kDa) PRKCB 5579 16 23847322 24231932 protein kinase C, beta PTEN 5728 10 89622870 89731687 phosphatase and tensin homolog PTPRD 5789 9 8314246 10612723 protein tyrosine phosphatase, receptor type, D PTPRJ 5795 11 48002113 48189670 protein tyrosine phosphatase, receptor type, J RAB3IP 117177 12 70132461 70216984 RAB3A interacting protein RAI1 10743 17 17584787 17714767 retinoic acid induced 1 RASAL2 9462 1 178062864 178448644 RAS protein activator like 2 RASIP1 54922 19 49223844 49243978 Ras interacting protein 1 RASL10B 91608 17 34058668 34070540 RAS-like, family 10, member B RAVER2 55225 1 65210778 65298915 ribonucleoprotein, PTB-binding 2 RGS10 6001 10 121259340 121302220 regulator of G-protein signaling 10 RNF157 114804 17 74138534 74236454 ring finger protein 157 ROBO1 6091 3 78646390 79816965 roundabout, axon guidance receptor, homolog 1 (Drosophila) RSRC1 51319 3 157823644 158263519 arginine/serine-rich coiled-coil 1 RXFP1 59350 4 159236463 159574524 relaxin/insulin-like family peptide receptor 1 S1PR3 1903 9 91606362 91619925 sphingosine-1-phosphate receptor 3 SEMA3E 9723 7 82993222 83278326 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E SEMA4G 57715 10 102729275 102745628 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G SERGEF 26297 11 17809595 18034709 secretion regulating guanine nucleotide exchange factor SGMS2 166929 4 108745719 108836203 sphingomyelin synthase 2 SH3PXD2B 285590 5 171752185 171881527 SH3 and PX domains 2B SIRPD 128646 20 1514897 1539489 signal-regulatory protein delta SLC17A3 10786 6 25833294 25882514 solute carrier family 17 (organic anion transporter), member 3 SLC25A16 8034 10 70237756 70287231 solute carrier family 25 (mitochondrial carrier), member 16 SLC25A25 114789 9 130830480 130871524 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 SLC39A8 64116 4 103172198 103352415 solute carrier family 39 (zinc transporter), member 8 SLC39A9 55334 14 69864732 69929105 solute carrier family 39, member 9 SLC4A11 83959 20 3208063 3219836 solute carrier family 4, sodium borate transporter, member 11 SLC4A4 8671 4 72053003 72437804 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 SLC6A14 11254 X 116436579 116461458 solute carrier family 6 (amino acid transporter), member 14 SLC7A2 6542 8 17354597 17428082 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 SMTN 6525 22 31460091 31500743 smoothelin SMURF2 64750 17 62538413 62658186 SMAD specific E3 ubiquitin protein ligase 2 SNX29 92017 16 12070594 12668146 sorting nexin 29 SOBP 55084 6 107811162 107981357 sine oculis binding protein homolog (Drosophila) SORCS3 22986 10 106400859 107024993 sortilin-related VPS10 domain containing receptor 3 SPDEF 25803 6 34505579 34524110 SAM pointed domain containing ETS transcription factor SPPL2B 56928 19 2328614 2355099 signal peptide peptidase like 2B SSH2 85464 17 27952956 28257294 slingshot protein phosphatase 2 STARD9 57519 15 42867857 43013179 StAR-related lipid transfer (START) domain containing 9 STAT2 6773 12 56735381 56753939 signal transducer and activator of transcription 2, 113kDa SYNPO 11346 5 149980642 150038782 synaptopodin TAOK1 57551 17 27717482 27878922 TAO kinase 1 TBC1D10B 26000 16 30368423 30381585 TBC1 domain family, member 10B TET1 80312 10 70320413 70454239 tet methylcytosine dioxygenase 1 THRB 7068 3 24158651 24536773 thyroid hormone receptor, beta TMCC1 23023 3 129366635 129612419 transmembrane and coiled-coil domain family 1 TMED3 23423 15 79603404 79704334 transmembrane emp24 protein transport domain containing 3 TMEM135 65084 11 86748886 87034800 transmembrane protein 135 TMPRSS15 5651 21 19641433 19858197 transmembrane protease, serine 15 TRAFD1 10906 12 112563305 112591407 TRAF-type zinc finger domain containing 1 TUBG2 27175 17 40811323 40819024 tubulin, gamma 2 USP24 23358 1 55532032 55680786 ubiquitin specific peptidase 24 USP28 57646 11 113668596 113746292 ubiquitin specific peptidase 28 UTRN 7402 6 144606837 145174170 utrophin VKORC1L1 154807 7 65338254 65424550 vitamin K epoxide reductase complex, subunit 1-like 1 VPS13A 23230 9 79792269 80036457 vacuolar protein sorting 13 homolog A (S. cerevisiae) WAC 51322 10 28821422 28912041 WW domain containing adaptor with coiled-coil WHSC1L1 54904 8 38127215 38239790 Wolf-Hirschhorn syndrome candidate 1-like 1 WIPF2 147179 17 38375556 38440388 WAS/WASL interacting protein family, member 2 ZCCHC6 79670 9 88902648 88969369 zinc finger, CCHC domain containing 6 ZNF350 59348 19 52467596 52490109 zinc finger protein 350 ZNF516 9658 18 74069644 74207146 zinc finger protein 516 ZNF627 199692 19 11670189 11729950 zinc finger protein 627 ZNF704 619279 8 81540686 81787016 zinc finger protein 704 top

© 2015 Cai Laboratory.  Last updated on 13 Mar 2018