ChromothripsisDB: a curated database of chromothripsis
 
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  Fusion Gene
  PubMed ID: 25351503 Case ID: OESO_1712 Disease: Esophageal adenocarcinoma Genome Assembly: GRCh37/hg19
Gene Symbol 1 Chromosome1 Description 1 Gene Symbol 2 Chromosome2 Description 2
TTYH3 7 tweety family member 3 SPTB 14 spectrin, beta, erythrocytic
DFNA5 7 deafness, autosomal dominant 5 EPDR1 7 ependymin related 1
ORC5 7 origin recognition complex, subunit 5 MUC19 12 mucin 19, oligomeric
 
 
  Affected Gene
  PubMed ID: 25351503 Case ID: OESO_1712 Disease: Esophageal adenocarcinoma Genome Assembly: GRCh37/hg19
Gene Symbol Entrez Gene Chromosome Start End Description
FHIT 2272 3 59735036 61237133 fragile histidine triad
KRT8 3856 12 53290977 53343738 keratin 8, type II
OXR1 55074 8 107282473 107764922 oxidation resistance 1
WWOX 51741 16 78133310 79246564 WW domain containing oxidoreductase
MACROD2 140733 20 13976015 16033842 MACRO domain containing 2
TNKS 8658 8 9413424 9639856 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
GMFG 9535 19 39818993 39833012 glia maturation factor, gamma
TTC28 23331 22 28374004 29075853 tetratricopeptide repeat domain 28
SMYD3 64754 1 245912642 246670614 SET and MYND domain containing 3
GMDS 2762 6 1624041 2245926 GDP-mannose 4,6-dehydratase
SLC25A21 89874 14 37147636 37642071 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
POLH 5429 6 43543887 43586701 polymerase (DNA directed), eta
RSPH9 221421 6 43612783 43640336 radial spoke head 9 homolog (Chlamydomonas)
PTCHD4 442213 6 47845764 48036425 patched domain containing 4
ADAP1 11033 7 937540 995043 ArfGAP with dual PH domains 1
PTPRD 5789 9 8314246 10612723 protein tyrosine phosphatase, receptor type, D
RABGAP1L 9910 1 174128548 174964445 RAB GTPase activating protein 1-like
CNTNAP2 26047 7 145813453 148118090 contactin associated protein-like 2
LRP1B 53353 2 140988992 142889270 low density lipoprotein receptor-related protein 1B
RYR1 6261 19 38924339 39078204 ryanodine receptor 1 (skeletal)
STEAP1B 256227 7 22459063 22672544 STEAP family member 1B
ZDHHC11 79844 5 710471 851101 zinc finger, DHHC-type containing 11
WDR70 55100 5 37379314 37753537 WD repeat domain 70
FGGY 55277 1 59762310 60233347 FGGY carbohydrate kinase domain containing
OPCML 4978 11 132284871 133402414 opioid binding protein/cell adhesion molecule-like
CHST12 55501 7 2443223 2474242 carbohydrate (chondroitin 4) sulfotransferase 12
FAM153A 285596 5 177134982 177210399 family with sequence similarity 153, member A
PTPRB 5787 12 70910630 71031220 protein tyrosine phosphatase, receptor type, B
SAE1 10055 19 47616531 47713886 SUMO1 activating enzyme subunit 1
DYRK1A 1859 21 38738092 38889753 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
PRUNE2 158471 9 79226292 79521003 prune homolog 2 (Drosophila)
FSTL5 56884 4 162305049 163085187 follistatin-like 5
THSD7B 80731 2 137523115 138435287 thrombospondin, type I, domain containing 7B
SUPT3H 8464 6 44777054 45345690 suppressor of Ty 3 homolog (S. cerevisiae)
NRXN3 9369 14 78708734 80330762 neurexin 3
C1orf158 93190 1 12806163 12823847 chromosome 1 open reading frame 158
HMCN1 83872 1 185703683 186160085 hemicentin 1
ESRRG 2104 1 216676588 217311097 estrogen-related receptor gamma
PHC1 1911 12 9066492 9094063 polyhomeotic homolog 1 (Drosophila)
SLC38A4 55089 12 47158546 47226191 solute carrier family 38, member 4
SPTB 6710 14 65213002 65346601 spectrin, beta, erythrocytic
IL16 3603 15 81451916 81605104 interleukin 16
SCNN1G 6340 16 23194036 23228204 sodium channel, non voltage gated 1 gamma subunit
PDE4A 5141 19 10527449 10580305 phosphodiesterase 4A, cAMP-specific
GYS1 2997 19 49471382 49496567 glycogen synthase 1 (muscle)
ZSCAN5A 79149 19 56732681 56879752 zinc finger and SCAN domain containing 5A
REL 5966 2 61108656 61158745 v-rel avian reticuloendotheliosis viral oncogene homolog
PPP1R1C 151242 2 182818968 182996125 protein phosphatase 1, regulatory (inhibitor) subunit 1C
SPOCK1 6695 5 136310987 136934068 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
CDC5L 988 6 44355262 44418163 cell division cycle 5-like
GPR115 221393 6 47653600 47689757 G protein-coupled receptor 115
IMPG1 3617 6 76630832 76782395 interphotoreceptor matrix proteoglycan 1
FRK 2444 6 116252312 116381921 fyn-related Src family tyrosine kinase
ECT2L 345930 6 139117063 139225207 epithelial cell transforming 2 like
SMC5 23137 9 72873937 72969804 structural maintenance of chromosomes 5
DMD 1756 X 31119219 33339609 dystrophin
PARK2 5071 6 161768452 163148803 parkin RBR E3 ubiquitin protein ligase
GPC5 2262 13 92050929 93519490 glypican 5
DLG2 1740 11 83166055 85338966 discs, large homolog 2 (Drosophila)
PACRG 135138 6 163148164 163736524 PARK2 co-regulated
EYS 346007 6 64429876 66417118 eyes shut homolog (Drosophila)
LHFPL3 375612 7 103969104 104549001 lipoma HMGIC fusion partner-like 3
TIAM2 26230 6 155153831 155578857 T-cell lymphoma invasion and metastasis 2
DST 667 6 56322785 56819426 dystonin
TCF12 6938 15 57210821 57591479 transcription factor 12
ERBB4 2066 2 212240446 213403565 erb-b2 receptor tyrosine kinase 4
CHRAC1 54108 8 141521397 141527236 chromatin accessibility complex 1
ABCC10 89845 6 43395104 43418168 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ICK 22858 6 52866077 52926600 intestinal cell (MAK-like) kinase
DCAF10 79269 9 37800499 37867663 DDB1 and CUL4 associated factor 10
GSR 2936 8 30535583 30585443 glutathione reductase
FAM163A 148753 1 179712298 179785333 family with sequence similarity 163, member A
SMARCA4 6597 19 11071598 11176071 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
FXR1 8087 3 180585929 180700541 fragile X mental retardation, autosomal homolog 1
HERC2 8924 15 28356186 28567298 HECT and RLD domain containing E3 ubiquitin protein ligase 2
PRMT8 56341 12 3490515 3703139 protein arginine methyltransferase 8
TIAM1 7074 21 32490734 32932290 T-cell lymphoma invasion and metastasis 1
NPSR1 387129 7 34697851 34917944 neuropeptide S receptor 1
USH2A 7399 1 215796236 216596738 Usher syndrome 2A (autosomal recessive, mild)
CACNB2 783 10 18429606 18830798 calcium channel, voltage-dependent, beta 2 subunit
KCNQ5 56479 6 73331520 73908574 potassium channel, voltage gated KQT-like subfamily Q, member 5
ABCA13 154664 7 48211055 48687092 ATP-binding cassette, sub-family A (ABC1), member 13
GLIS3 169792 9 3824127 4348392 GLIS family zinc finger 3
ZRANB2 9406 1 71528974 71546980 zinc finger, RAN-binding domain containing 2
RGSL1 353299 1 182419256 182529734 regulator of G-protein signaling like 1
NMT2 9397 10 15144583 15210692 N-myristoyltransferase 2
SLC1A2 6506 11 35272753 35441610 solute carrier family 1 (glial high affinity glutamate transporter), member 2
M6PR 4074 12 9092959 9102551 mannose-6-phosphate receptor (cation dependent)
KLRG1 10219 12 9102640 9163356 killer cell lectin-like receptor subfamily G, member 1
KIAA1467 57613 12 13197218 13295455 KIAA1467
FAR2 55711 12 29302036 29493913 fatty acyl CoA reductase 2
MUC19 283463 12 40787197 40964632 mucin 19, oligomeric
PCID2 55795 13 113831891 113863029 PCI domain containing 2
AKAP13 11214 15 85923802 86292586 A kinase (PRKA) anchor protein 13
ITGAM 3684 16 31271311 31344213 integrin, alpha M (complement component 3 receptor 3 subunit)
TYK2 7297 19 10461209 10491352 tyrosine kinase 2
LTBP4 8425 19 41098789 41135725 latent transforming growth factor beta binding protein 4
FAM83E 54854 19 49104067 49118111 family with sequence similarity 83, member E
RASIP1 54922 19 49223844 49243978 Ras interacting protein 1
ZNF264 9422 19 57702868 57724724 zinc finger protein 264
PDE1A 5136 2 183004763 183387919 phosphodiesterase 1A, calmodulin-dependent
COL4A4 1286 2 227867427 228028829 collagen, type IV, alpha 4
CELSR1 9620 22 46756731 46933067 cadherin, EGF LAG seven-pass G-type receptor 1
GRAMD4 23151 22 46971909 47075688 GRAM domain containing 4
STK32B 55351 4 5053169 5502725 serine/threonine kinase 32B
RAPGEF2 9693 4 160025330 160281321 Rap guanine nucleotide exchange factor (GEF) 2
CPE 1363 4 166282346 166419472 carboxypeptidase E
ZDHHC11B 653082 5 710475 767067 zinc finger, DHHC-type containing 11B
SLC6A3 6531 5 1392909 1445545 solute carrier family 6 (neurotransmitter transporter), member 3
PDZD2 23037 5 31639517 32111037 PDZ domain containing 2
TARS 6897 5 33440802 33469644 threonyl-tRNA synthetase
CEP120 153241 5 122680579 122759286 centrosomal protein 120kDa
KLHL3 26249 5 136953189 137071779 kelch-like family member 3
HIST1H2BN 8341 6 27806323 27823487 histone cluster 1, H2bn
LRFN2 57497 6 40359325 40555204 leucine rich repeat and fibronectin type III domain containing 2
MRPS10 55173 6 42174539 42185603 mitochondrial ribosomal protein S10
CNPY3 10695 6 42896938 42907025 canopy FGF signaling regulator 3
TTBK1 84630 6 43211418 43255997 tau tubulin kinase 1
TJAP1 93643 6 43445261 43474294 tight junction associated protein 1 (peripheral)
IL17A 3605 6 52051185 52055436 interleukin 17A
HMGCLL1 54511 6 55299167 55444012 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
HS3ST5 222537 6 114376750 114664209 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
REPS1 85021 6 139224630 139309398 RALBP1 associated Eps domain containing 1
UST 10090 6 149068464 149398126 uronyl-2-sulfotransferase
AGPAT4 56895 6 161551011 161695093 1-acylglycerol-3-phosphate O-acyltransferase 4
TTYH3 80727 7 2671585 2704436 tweety family member 3
DFNA5 1687 7 24737972 24809244 deafness, autosomal dominant 5
EPDR1 54749 7 37723446 37991543 ependymin related 1
SFRP4 6424 7 37945543 38065297 secreted frizzled-related protein 4
ADAM22 53616 7 87563458 87832204 ADAM metallopeptidase domain 22
ORC5 5001 7 103766788 103848495 origin recognition complex, subunit 5
ATXN7L1 222255 7 105245514 105517050 ataxin 7-like 1
HIPK2 28996 7 139246316 139477577 homeodomain interacting protein kinase 2
DENND2A 27147 7 140218220 140373793 DENN/MADD domain containing 2A
ACO1 48 9 32384618 32454767 aconitase 1, soluble
PRSS3 5646 9 33750515 33799230 protease, serine, 3
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Chromothripsis database. 2025 Cai Laboratory